NOVELTY – The production of enantiometrically pure substituted benzodihydrofurans has processing based on a commercial aldehyde, for preparation of benzodihydrofuranic esters and acids. The catalyst (Dabco) permits asymmetric synthesis of the drug Efaroxan for use in Diabetes mellitus treatment, and is recuperated in the Baylis-Hillman adduct isolation process. EMBODIMENT – The stereogenic center present in Efaroxan is formed in the synthesis. USE – In physical chemistry.
B02 (Fused ring heterocyclics.)