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Nanostructured lipid carriers, formulations composed of natural lipids encapsulating essential oils in a stable and efficient way

Formulations based on structural and bioactive lipid matrices such as beeswax, palm, shea and cocoa butters

To develop natural compositions encapsulating essential oils with long-term stability is the main goal of several research areas. The problem is to keep the stability of the excipients and to allow the synergistic action of oils and nanoparticles. The researches from UNICAMP developed a new formulation, using nanostructured lipid carriers (NLC) composed of natural lipids such as beeswax, palm, shea, and cocoa butters stabilized by natural surfactants.

The new pharmaceutical form have multiple advantages over other formulations, by sustaining the release of these natural products with low toxicity to humans. Moreover, in the NLC composed of natural oils, the functional properties of excipients are extended to the formulation, explaining the anesthetic, bactericidal, antifungal and biopesticide actions observed, without the use of any synthetic, component.

MAIN BENEFITS AND CHARACTERISTICS OF THIS INVENTION:

Long-term stability for encapsulation
Functional and stable bioactive formulations
Several Intrinsic therapeutic actions

INVENTORS:

Eneida de Paula

• Ph.D and Full Professor in Biochemistry, associate researcher at Institute of Biology – UNICAMP
Lígia Nunes de Morais Ribeiro
UNICAMP
Simone Ramos de Castro
UNICAMP
Ludmilla David de Moura
UNICAMP
Marcelo Lancellotti
UNICAMP
Márcia Cristina Breitkreitz
UNICAMP
Viviane Aparecida Guilherme Damasio
UNICAMP
Gustavo Henrique Rodrigues da Silva
UNICAMP
André Ricardo de Lima Damasio
UNICAMP
Marcelo Ventura Rubio
UNICAMP
Leonardo Fernandes Fraceto
UNESP
Mônica Pascoli
UNESP
Felícia Pereira de Albuquerque
UNESP
Ricardo Antonio Polanczyk
UNESP
Daniel Junior de Andrade
UNESP
FACULTY/INSTITUTE:
Institute of Biology – IB – UNICAMP
Institute of Chemistry – IQ – UNICAMP
Faculty of Pharmaceutical Sciences – FCF – UNICAMP
PARTNERS:
São Paulo State University Júlio de Mesquita Filho – UNESP

PATENT’S STATUS:

Patent application at the INPI – Brazilian National Institute of Industrial Property (Brazilian Patent Office)
INTERNAL CODE: 1377_CLN NATURAL

MORE INFORMATION:

parcerias@inova.unicamp.br

+55 19 3521.2607 / 5013

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