Processo de produção de enxerto ósseo e enxerto ósseo assim obtido
Biotecnologia / Medicina
Pharmaceutical composition comprising a local anaesthetic and a carboxyvinyl polymer
NOVELTY – A pharmaceutical composition (C1), comprises at least one anesthetic and gelling agent, the composition having a minimum viscosity of 30 Pa.s, when subjected to a temperature of 5-50 degrees C. USE – In the dental treatment and dermatological treatment; and for treating pain (claimed). ADVANTAGE – The composition provides improved penetration of the anesthetic by maintaining the drug for a longer time and at a higher concentration on the action site, which increases the duration of anesthesia while reducing its toxicity, in addition to restricting the action of the drug to the application site. The maintenance of the drug for a longer time and at higher concentration on the action site is made possible as this anesthetic gel shows a smaller variation in its viscosity when subjected to a temperature increase resulting from the contact with the buccal mucosa. DETAILED DESCRIPTION – An INDEPENDENT CLAIM is included for obtaining pharmaceutical composition (C1) involving micronizing the local anesthetic); adding a levigating agent; adding a gelling agent; adding a preservative and a wetting agent; and adjusting pH, through the addition of an alkalizing agent.
Main Application Field
A96 (Medical, dental, veterinary, cosmetic.); B07 (General – tablets, dispensers, catheters (excluding drainage and angioplasty), encapsulation etc, but not systems for administration of blood or saline or IV feeding etc.); B05 (Other organics – aromatics, aliphatic, organo-metallics, compounds whose substituents vary such that they would be classified in several of B01 – B05.)
INVENTORS:
ROTOLO SILVA ANDRE LUIZ
MONTAN MICHELLE FRANZ
GROPPO FRANCISCO CARLOS
VOLPATO MARIA CRISTINA
RANALI JOSE
FRACETO LEONARDO FERNANDES
DE PAULA ENEIDA
