Combating of e.g. tumors by a hydrophobic compound consists of encapsulation of violacein to enhance its toxicity reduction capacity

NOVELTY – The combating of e.g. tumors by a hydrophobic compound comprises formulation of violacein encapsulated in beta-cyclodextrin conjugated with a gold nanoparticle via a specific dithiol. Also claimed is a process using the encapsulated violacein. The process employs in vitro cultures based on HL 60 leukemia cells and V79 fibroblasts respectively and a complex Au-S(CH2)6-S-beta-CD, without which violacein is less effective as regards V79 toxicity reduction. USE – In physical chemistry.

Main Application Field

A96 (Medical, dental, veterinary, cosmetic.); B02 (Fused ring heterocyclics.); B07 (General – tablets, dispensers, catheters (excluding drainage and angioplasty), encapsulation etc, but not systems for administration of blood or saline or IV feeding etc.)

INVENTORS:

ALVES OSVALDO LUIZ
GIMENEZ IARA DE FATIMA
AZEVEDO MARCELO MANTOVANI MART
CABALLERO NELSON EDUARDO DURAN
MELO PATRICIA DA SILVA

37_ANTIPARASITARIO

Patent number: BR200502657-A

PATENT STATUS:

For information contact Inova Unicamp

FOR ADDITIONAL INFORMATION:

parcerias@inova.unicamp.br

+55 (19) 3521-5207 / 2607