Composição Biocida e método para eliminação de corais invasores em condições subaquáticas
Química / Tecnologia Ambiental
Method for constructing an attenuated mutant strain of pathogenic bacteria, vaccine, vaccine vector and us
NOVELTY – Constructing an attenuated mutant strain of pathogenic bacteria involves expressing Gam protein, Bet and Exo of bacteriophage lambda present in plasmid pKD46, and promoting the recombination of linear DNA fragments target. HU gene is provided for encoding the recombination cassette for gene enhancement, and for elimination of accessory gene present in the recombination cassette. USE – Method for constructing an attenuated mutant strain of pathogenic bacteria of family Enterobacteriaceae, Vibrionaceae, Francisellaceae and Legionellaceae and Salmonella spp., Shigella spp., Escherichia spp., Yersinia spp., Vibrio and Salmonella enterica serovar Typhimurium (ST662) for use in vaccine vector for stimulating humoral or cellular immune response against an infection caused by a pathogenic bacterium and salmonellosis (all claimed).
Main Application Field
B04 (Natural products and polymers. Including testing of body fluids (other than blood typing or cell counting), pharmaceuticals or veterinary compounds of unknown structure, testing of microorganisms for pathogenicity, testing of chemicals for mutagenicity or human toxicity and fermentative production of DNA or RNA. General compositions.); C06 (Biotechnology – including plant genetics and veterinary vaccines.); D16 (Fermentation industry – including fermentation equipment, brewing, yeast production, production of pharmaceuticals and other chemicals by fermentation, microbiology, production of vaccines and antibodies, cell and tissue culture and genetic engineering.); B05 (Other organics – aromatics, aliphatic, organo-metallics, compounds whose substituents vary such that they would be classified in several of B01 – B05.); T01 (Digital Computers)
INVENTORS:
BROCCHI MARCELO
PIVETTA LUCIANE BENEDITA DUARTE
