Pharmaceutical Composition for vase control occlusion and its uses

NOVELTY – Bacterin vaccine preparation involves adding catecholamines (adrenaline 10-2000 micromolar) and autoinducers in vaccine culture medium, and then processing the obtained culture medium using quorum sensing bacterial communication system to obtain the desired product, where the catecholamines and autoinducers are added in the vaccine to increase the expression of antigens in enterotoxigenic Escherichia coli. The autoinducer is supernatant of culture medium (5-95%). USE – Method for preparing bacterin vaccine used for controlling colibacillosis in pigs caused by Escherichia coli (all claimed). ADVANTAGE – The method enables to prepare bacterin vaccine that is efficient, and contains catecholamines and autoinducers that ensures improved expression of antigens in enterotoxigenic Escherichia coli.

Main Application Field

B04 (Natural products and polymers. Including testing of body fluids (other than blood typing or cell counting), pharmaceuticals or veterinary compounds of unknown structure, testing of microorganisms for pathogenicity, testing of chemicals for mutagenicity or human toxicity and fermentative production of DNA or RNA. General compositions.); C06 (Biotechnology – including plant genetics and veterinary vaccines.); D16 (Fermentation industry – including fermentation equipment, brewing, yeast production, production of pharmaceuticals and other chemicals by fermentation, microbiology, production of vaccines and antibodies, cell and tissue culture and genetic engineering.)

INVENTORS:

COSTA FERNANDO FERREIRA
ZORZETTO NICOLA CONRAN
ALMEIDA CAMILA BONONI DE
FRENETTE PAUL S

580_HIDROXIUREIA

Patent number: BR102012016109-A2

PATENT STATUS:

For information contact Inova Unicamp

FOR ADDITIONAL INFORMATION:

parcerias@inova.unicamp.br

+55 (19) 3521-5207 / 2607