Microorganisms and process for producing n-propanol

Backlog Biotecnologia Química Química macromolecular, Polímeros Química orgânica fina

Microorganisms and process for producing n-propanol

NOVELTY – Producing n-propanol comprises: providing a suitable carbon source for fermentation by a microorganism expressing the dicarboxylic acid pathway, reducing equivalents, and at least one gene coding for an enzyme that catalyzes the conversion of propionate/propionyl-coenzyme A (CoA) into n-propanol; contacting the carbon source and reducing equivalents with the microorganism under conditions favorable for the production of n-propanol by the microorganism, thus a fermentation broth is produced; and recovering n-propanol from the fermentation broth. USE – The method is useful to produce n-propanol, which is useful to produce propylene, where the propylene is useful to give polypropylene (all claimed) to yield a bioplastic, and thermoplastic resins (for applications including rigid or flexible packaging materials, blow molding and injection molding). ADVANTAGE – The method provides: n-propanol (which has 100% of biobased content and contributes to reduce greenhouse gas emission) with high yield, propylene and polypropylene in a cost-effective manner; and iso-propanol and/or ethanol to maximize the carbon yield. DETAILED DESCRIPTION – INDEPENDENT CLAIMS are also included for: (1) a microorganism useful in the n-propanol production method; (2) producing propylene comprising either: dehydrating n-propanol produced by the above method in the same reactor to produce propylene; or dehydrating in the same reactor n-propanol and isopropanol and/or ethanol; and (3) producing polypropylene comprising polymerizing the produced propylene. DESCRIPTION OF DRAWING(S) – The figure shows the integrated process to produce n-propanol in the presence of reducing equivalents externally supplied through the use of a bioelectrical reactor.

Main Application Field

A41 (Monomers and Condensants These are also included in Section E.); A17 (Polymers of unsubstituted aliphatic monoolefins; including polyethylene.); A92 (Packaging and containers – including ropes and nets.); D16 (Fermentation industry – including fermentation equipment, brewing, yeast production, production of pharmaceuticals and other chemicals by fermentation, microbiology, production of vaccines and antibodies, cell and tissue culture and genetic engineering.); E17 (Other aliphatics.)

INVENTORS:

PEREIRA GONCALO AMARANTE GUIMARAES
PEREZ JOHANA RINCONES
CARAZZOLLE MARCELO FALSARELLA
ZEIDLER ANE FERNANDA BERALDI
PARIZZI LUCAS PEDERSEN
CALDERON LUIGE ARMANDO LLERENA
GRASSI MARIA CAROLINA DE BARROS
LUNARDI INES
DE OLIVEIRA LUCIANA GONZAGA
RODRIGUES JOSE AUGUSTO ROSARIO
MORAN PAULO JOSE SAMENHO
MORSCHBACKER ANTONIO LUIZ RIBEIRO DE CASTRO
ROZA LUIZA
ANDRADE MARCIO HENRIQUE DOS SANTOS

603_PROPILENO

Patent number: WO2011029166-A1;CA2772292-A1;AU2010292910-A1;AU2010292910-A2;EP2464735-A1;KR2012083391-A;MX2012002995-A1;JP2013503647-W;US2013095542-A1;ZA201201945-A;AU2010292910-B2;MX325893-B;IN201202878-P1;BR112012005424-A2

PATENT STATUS:

GRANTED

FOR ADDITIONAL INFORMATION:

parcerias@inova.unicamp.br

+55 (19) 3521-5207 / 2607

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