NOVELTY – The production of amino alcohols for antibiotics comprises five-stage processing for synthesis of chloramphenicol, fluoroamphenicol and thiamphenicol. Also claimed is a process using the products. The process uses catalyst (DABCO) for production of two stereochemical centres of the antibiotic, and preparation of enantiomerically pure products. USE – In industrial chemistry.
B05 (Other organics – aromatics, aliphatic, organo-metallics, compounds whose substituents vary such that they would be classified in several of B01 – B05.)