NOVELTY – Mimicry kit comprises a co-culturing device, immortalized human glial cells, immortalized human endothelial cells and human pro-myelocytic cell. USE – Mimicry kit used for studying pathophysiological and pharmacological conditions occurring at the interface between systemic circulation and central nervous system involving passage of pathogens and drugs through blood-brain barrier. ADVANTAGE – The mimicry kit enables the analysis of neurotoxic compounds such as drugs and medicines. DETAILED DESCRIPTION – An INDEPENDENT CLAIM is included for a method for constructing kit, which involves: (A) cultivating cell lines and trypsinizing immortalized human glial cell; (B) differentiating human pro-myelocytic lineage; (C) centrifuging human pro-myelocytic lineage; and (D) transferring cell to co-culture device and then incubating the cells.
B04 (Natural products and polymers. Including testing of body fluids (other than blood typing or cell counting), pharmaceuticals or veterinary compounds of unknown structure, testing of microorganisms for pathogenicity, testing of chemicals for mutagenicity or human toxicity and fermentative production of DNA or RNA. General compositions.); D16 (Fermentation industry – including fermentation equipment, brewing, yeast production, production of pharmaceuticals and other chemicals by fermentation, microbiology, production of vaccines and antibodies, cell and tissue culture and genetic engineering.); S03 (Scientific Instrumentation)